Graphene, boron nitride, dichalcogenides and other inorganic 2D layered materials (2DLM) have atomically thin structure with unique electrical, mechanical, thermal, and optical properties, and have already been extensively explored for electronics, sensing, catalysis and biomedical applications. On the other hand, in the polymer world, there is an emerging class of 2D polymers with analog structure to 2D layered materials.
The project consists of designing and fabricating photo-programmable microstructures consist of microfluidic ecosystem and interacting biological species. The biohybrid system exploits power, sensing and navigation of the biological components and the sensivity of the photo-active parts to tune the dynamics of species within the micro-ecosystem.
We use a bioengineering approach to develop biomimetic three-dimensional tumor models to understand the disease biology and test and identify novel treatments. We are an interdisciplinary team of graduate and undergraduate students tackling a very significant problem using a combination of biomedical and biological approaches.
The Earth is about 4.56 billion years old and the earliest evidence of life is at approximately 3.8 billion years ago. How life originated from a planet composed of only minerals, dissolved elements, and simple organic molecules is one of the great questions of scientific inquiry. Life requires complex biomolecules, such as proteins, RNA and DNA, to maintain a cell and for reproduction.
Understanding the physical and chemical interactions between ice and materials is of interest in order to tune adhesion and friction on ice to meet various material demands. For example, it is important for tires to have good traction on ice and snow, and low ice adhesion coatings are needed for applications on aircraft, power lines, wind turbines, and costal structures/ships. This project aims to find specific material surface properties in nature that have been evolved to either increase or decrease ice nucleation, adhesion, and/or friction.
In this project, students will conduct experimental testing and computational analysis at Prof. K.T. Tan’s Advanced Metacomposites Laboratory to investigate the amazing bone structure of biological models with flight capability.
The concept of biomimicry is solving problems and creating new opportunities through understanding and applying biological models. Very often, innovation inspired by nature and careful examination of the natural world are potential ways to seek solution to real-world problems. In this project, students will conduct experimental testing and computational analysis at Prof. K.T. Tan’s Advanced Metacomposites Laboratory to investigate the amazing structure of biological models.
Mechanical stress is ubiquitously present in materials and biological systems, and the force-induced bond scission and materials failure have been extensively studied. In recent years, utilizing mechanical force to do targeted and constructive chemistry, largely fueled by the concept of mechanophore, i.e., stress-responsive moiety, has become a new trend.
Our lab focuses on tissue engineering methods to improve nerve regeneration. Undergraduates working on these projects have focused on material or cellular aspects, depending on interest and skill. We work both in vivo and in vitro, on optic and peripheral nerve, and both neural and embryonic stem cells.